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Ferroptosis and RF exhibit a mutually reinforcing relationship: in CKD renal tissues, lipid peroxidation, necroinflammation, and iron overload damage parenchymal cells, driving fibrotic accumulation (189)

Cells were split into two 50-ml conical tubes before centrifugation at room temperature and 200 x g for 5 min

As -KG enters the TCA cycle, it gets oxidized to generate succinate and fumarate, which are cancer metabolites that produce ATP, NADH, and FADH2 [34] (Fig

It seems that the association between zinc homeostasis and brown adipose tissue, thermogenesis, and inflammation may contribute to the development of new therapies for obesity and metabolic syndrome